Scientist/Sr. Scientist - Cardiovascular Biology (m/f/d)

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The Team

Dewpoint Therapeutics translates condensate biology into much-needed medicines. Biomolecular condensates are transforming our understanding of biology, and our highly collaborative team is at the forefront of efforts to harness this shift for drug discovery. With deep and diverse expertise in medicine, biology, AI, chemistry, physics, and more, we aim to discover life-changing therapeutics for patients who currently have few or no treatment options. Together, we are leveraging a transformative shift in the understanding of cellular biology to discover and advance breakthrough therapeutics for the toughest diseases.

From Our Recent DEI Survey, 84% Of The Company Responded And We Are Proud Of What Our Team Members Shared

In 30 months, we have grown rapidly to over 100 colleagues and are truly global, with offices in Boston, Dresden, and Berlin and team members in five different countries. We are also diverse in many ways.

• Together we speak 14 languages and come from 18 birth countries.
• Half of us are introverts and half are extraverts.
• Were nearly split evenly between being reserved and being assertive.
• Two thirds of us like to ponder before making decisions and a third of us prefer rapid decision-making.
• We represent the full spectrum of gender identities and sexual orientations.
• 25% of us are neurodiverse or differently physically abled.
• 70% of us are Millennials.
• We are nearly equally split between those who joined us < 7 months, 7-12 months, and over a year.
  

We are also uniquely accomplished in our careers before Dewpoint and in our work together. Collectively, our team members have brought 51 drugs to market and published almost a thousand paper. At Dewpoint, we have forged four important partnerships, including three with major pharmaceutical companies. We have raised $147M in venture financing and are making significant investments in our people, science, and platform.

The Opportunity

We are searching for an innovative cardiovascular Scientist/Sr. Scientist to work in the laboratory and drive our condensate-focused drug discovery efforts. You will have a strong scientific background in cardiovascular biology, cell and molecular biology, and experience in optimizing and validating assay for cardiovascular drug discovery efforts. This position requires a strong cardiovascular physiology background. Experience in performing target validation and cellular mechanism of action studies is preferred. You will work closely with cross-functional teams to further the discovery efforts.

In this position youll be part of an energizing and supportive startup culture engaged in continuous learning, and part of an exceptional international team. This role is based at our site in Dresden’s BioInnovation Center. Dewpoint offers competitive salary and benefits.

The Role

In this role you will...

• Independently design, develop, and validate cell-based assays for implementation in cardiovascular research and drug discovery efforts
• Implement work plans over agreed timelines such that the objectives of the project are met, including delivery of more than one agreed area of work in parallel where appropriate
• Lead one or more aspects of scientific subject area within the team
• Achieve personal scientific visibility through project contributions and internal presentations at departmental or functional meetings; and external scientific visibility through poster & oral conference presentations and authorship on peer-reviewed publications
• Mentor, motivate, and inspire other team members at all levels
• Become a valuable contributor to other initiatives as they arise in our fast paced, startup environment

Requirements

To do that you will need...

• PhD in cardiovascular biology, molecular biology, cell biology, or a related field or a BS/MS with 5+ years of experience
• Experience in independently designing and executing various cell-based assays
• Strong expertise in working with different cell types, including iPSC-derived cardiomyocytes and primary cells
• Hands on experience in calcium flux measurements and analyzing electrophysiology data
• Experience in diverse molecular biology techniques such as RT-PCR, CRISPR, siRNA, viral vectors
• Excellent organizational skills and ability to balance multiple objectives with good follow through and delivery in a timely manner
• Ability to collaborate in a multidisciplinary and dynamic environment and experience in mentoring and leading scientific teams
• Ability to communicate effectively in English, the shared language of our multicultural team
  

It is nice but not essential that you also have...

• Understanding of diverse rodent and in vitro models of cardiomyocyte health, heart failure, genetic, surgical, or pharmacological modulation
• Confocal microscopy and image processing experience
• Experience in computational analysis of biological data (i.e. NGS or proteomics)
• Experience in driving target identification and validation to enable drug discovery efforts

Interested?

Please be sure to include a customized cover letter andcurrent resume. Since we work hard to establish a personal connection with qualified candidates, only those who meet the requirements will be contacted personally.

We assure that all correspondence will be held in the strictest of confidence.

Thank you for your interest in Dewpoint. We look forward to hearing from candidates who can join us and contribute their vision, strategies, and insights to our growing organization.

About Dewpoint

Dewpoint Therapeutics is the first company founded to apply the emerging discipline of biomolecular condensates to drug discovery. Dewpoint believes that a vast range of conditions have pathways that are regulated by condensates or arise from the dysfunction of condensates including cancer, neurodegeneration, and metabolic disease. Dewpoint scientists are working in Boston, MA, and Dresden and Frankfurt, Germany, to translate condensate biology into treatments for the toughest diseases.

Dewpoint Therapeutics is an equal opportunity employer committed to the principles of non-discrimination in the workplace. Candidates will not be discriminated against on the basis of age, race, creed, color, religion, sex, sexual orientation, national origin, disability, marital status, or any other basis prohibited by federal, state, or local law.

Dewpoint Therapeutics has an anti-hate policy in place, along with an active staff-led Diversity, Equity, and Inclusion Committee sponsored by the CEO.

Please, no solicitations by agencies.

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